Key Role of STAT4 Deficiency in the Hematopoietic Compartment in Insulin Resistance and Adipose Tissue Inflammation

Visceral adipose tissue (AT) inflammation is linked to the complications of obesity, including insulin resistance (IR) and type 2 diabetes. Recent data from our lab showed that germline deficiency in STAT4 reduces inflammation and improves IR in obese mice. The objective of this study was to determi...

Full description

Bibliographic Details
Main Authors: Anca D. Dobrian, Kaiwen Ma, Lindsey M. Glenn, Margaret A. Hatcher, Bronson A. Haynes, Eric J. Lehrer, Mark H. Kaplan, Jerry L. Nadler
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2017/5420718