Carbon Monoxide Releasing Molecule-2-Upregulated ROS-Dependent Heme Oxygenase-1 Axis Suppresses Lipopolysaccharide-Induced Airway Inflammation

Carbon Monoxide Releasing Molecule-2-Upregulated ROS-Dependent Heme Oxygenase-1 Axis Suppresses Lipopolysaccharide-Induced Airway Inflammation

The up-regulation of heme oxygenase-1 (HO-1) is mediated through nicotinamaide adenine dinucleotide phosphate (NADPH) oxidases (Nox) and reactive oxygen species (ROS) generation, which could provide cytoprotection against inflammation. However, the molecular mechanisms of carbon monoxide-releasing m...

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Bibliographic Details
Main Authors: Chih-Chung Lin, Li-Der Hsiao, Rou-Ling Cho, Chuen-Mao Yang
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
CORM-2
NADPH oxidase
ROS
AP-1
HO-1
Online Access:https://www.mdpi.com/1422-0067/20/13/3157

Internet

https://www.mdpi.com/1422-0067/20/13/3157

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