Feasibility of real-time in vivo 89Zr-DFO-labeled CAR T-cell trafficking using PET imaging.

Feasibility of real-time in vivo 89Zr-DFO-labeled CAR T-cell trafficking using PET imaging.

INTRODUCTION:Chimeric antigen receptor (CAR) T-cells have been recently developed and are producing impressive outcomes in patients with hematologic malignancies. However, there is no standardized method for cell trafficking and in vivo CAR T-cell monitoring. We assessed the feasibility of real-time...

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Main Authors: Suk Hyun Lee, Hyunsu Soh, Jin Hwa Chung, Eun Hye Cho, Sang Ju Lee, Ji-Min Ju, Joong Hyuk Sheen, Hyori Kim, Seung Jun Oh, Sang-Jin Lee, Junho Chung, Kyungho Choi, Seog-Young Kim, Jin-Sook Ryu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223814

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https://doi.org/10.1371/journal.pone.0223814

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