5-Fluorouracil: Mechanisms of Resistance and Reversal Strategies

The purpose of this work is to review the published studies on the mechanisms of action and resistance of 5-fluorouracil. The review is divided into three main sections: mechanisms of anti-tumor action, studies of the resistance to the drug, and procedures for the identification of new genes involve...

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Bibliographic Details
Main Authors: Wei-Shan Chen, Sheng-Jie Xu, Ying Yin, Ning Zhang
Format: Article
Language:English
Published: MDPI AG 2008-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/13/8/1551/