The Role Played by Mitochondria in FcεRI-Dependent Mast Cell Activation

Mast cells play a key role in the regulation of innate and adaptive immunity and are involved in pathogenesis of many inflammatory and allergic diseases. The most studied mechanism of mast cell activation is mediated by the interaction of antigens with immunoglobulin E (IgE) and a subsequent binding...

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Bibliographic Details
Main Authors: Maria A. Chelombitko, Boris V. Chernyak, Artem V. Fedorov, Roman A. Zinovkin, Ehud Razin, Lakhsmi Bhargavi Paruchuru
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
IgE
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.584210/full