Epigenetic Regulation of Processes Related to High Level of Fibroblast Growth Factor 21 in Obese Subjects

Epigenetic Regulation of Processes Related to High Level of Fibroblast Growth Factor 21 in Obese Subjects

We hypothesised that epigenetics may play an important role in mediating fibroblast growth factor 21 (FGF21) resistance in obesity. We aimed to evaluate DNA methylation changes and miRNA pattern in obese subjects associated with high serum FGF21 levels. The study included 136 participants with BMI 2...

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Bibliographic Details
Main Authors: Teresa Płatek, Anna Polus, Joanna Góralska, Urszula Raźny, Agnieszka Dziewońska, Agnieszka Micek, Aldona Dembińska-Kieć, Bogdan Solnica, Małgorzata Malczewska-Malec
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Genes
Subjects:
FGF21
obesity
glucose and lipid metabolism
DNA methylation
microRNA
Online Access:https://www.mdpi.com/2073-4425/12/2/307

Internet

https://www.mdpi.com/2073-4425/12/2/307

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