A Genome-Wide Screen for Genes Affecting Spontaneous Direct-Repeat Recombination in Saccharomyces cerevisiae

A Genome-Wide Screen for Genes Affecting Spontaneous Direct-Repeat Recombination in Saccharomyces cerevisiae

Homologous recombination is an important mechanism for genome integrity maintenance, and several homologous recombination genes are mutated in various cancers and cancer-prone syndromes. However, since in some cases homologous recombination can lead to mutagenic outcomes, this pathway must be tightl...

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Bibliographic Details
Main Authors: Daniele Novarina, Ridhdhi Desai, Jessica A. Vaisica, Jiongwen Ou, Mohammed Bellaoui, Grant W. Brown, Michael Chang
Format: Article
Language:English
Published: Oxford University Press 2020-06-01
Series:G3: Genes, Genomes, Genetics
Subjects:
homologous recombination
direct repeat
functional genomics
saccharomyces cerevisiae
genome stability
dna damage
dna repair
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.120.401137

Internet

http://g3journal.org/lookup/doi/10.1534/g3.120.401137

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