Rational Development of Liposomal Hydrogels: A Strategy for Topical Vaginal Antiretroviral Drug Delivery in the Context of HIV Prevention

Rational Development of Liposomal Hydrogels: A Strategy for Topical Vaginal Antiretroviral Drug Delivery in the Context of HIV Prevention

HIV/AIDS stands as a global burden, and vaginal microbicides constitute a promising strategy for topical pre-exposure prophylaxis. Preceding the development of a microbicide containing tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC), in silico and in vitro studies were performed to evalu...

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Bibliographic Details
Main Authors: Maria J. Faria, Raul Machado, Artur Ribeiro, Hugo Gonçalves, Maria Elisabete C. D. Real Oliveira, Teresa Viseu, José das Neves, Marlene Lúcio
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Pharmaceutics
Subjects:
drug release
emtricitabine
hydrogels
liposomes
microbicides
nanomedicine
tenofovir disoproxil fumarate
topical PrEP
Online Access:https://www.mdpi.com/1999-4923/11/9/485

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https://www.mdpi.com/1999-4923/11/9/485

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