Glibenclamide Mimics Metabolic Effects of Metformin in H9c2 Cells

Glibenclamide Mimics Metabolic Effects of Metformin in H9c2 Cells

Background: Sulfonylureas, such as glibenclamide, are antidiabetic drugs that stimulate beta-cell insulin secretion by binding to the sulfonylureas receptors (SURs) of adenosine triphosphate-sensitive potassium channels (KATP). Glibenclamide may be also cardiotoxic, this effect being ascribed to int...

Full description

Bibliographic Details
Main Authors: Barbara Salani, Silvia Ravera, Patrizia Fabbi, Silvano Garibaldi, Mario Passalacqua, Claudio Brunelli, Davide Maggi, Renzo Cordera, Pietro Ameri
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Glibenclamide
Metformin
ATP
Cardiomyocyte
H9c2
Metabolism
Online Access:https://www.karger.com/Article/FullText/481638

Internet

https://www.karger.com/Article/FullText/481638

Similar Items