T cell regeneration: an update on progress and challenges

Abstract. T cells play essential roles in antitumor therapy. Via gene engineering technique to enhance tumor-antigen specificity, patient peripheral blood-derived T cells (PBT) show encouraging clinical outcomes in treating certain blood malignancies. However, the high costs, functionality exhaustio...

Full description

Bibliographic Details
Main Authors: Rongqun Guo, Hongling Wu, Juan Du, Jinyong Wang
Format: Article
Language:English
Published: Wolters Kluwer Health 2020-01-01
Series:Blood Science
Online Access:http://journals.lww.com/10.1097/BS9.0000000000000037