Group A Streptococcus NAD-Glycohydrolase Inhibits Caveolin 1-Mediated Internalization Into Human Epithelial Cells

Group A Streptococcus NAD-Glycohydrolase Inhibits Caveolin 1-Mediated Internalization Into Human Epithelial Cells

Group A Streptococcus (GAS) invades epithelial cells causing persistent infection. GAS has a variety of effector proteins that modulate host systems to affect their survival in host environments. The main effector proteins of GAS are NAD-glycohydrolase (Nga) and streptolysin O (SLO). Although Nga ha...

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Bibliographic Details
Main Authors: Hirotaka Toh, Ching-Yu Lin, Shintaro Nakajima, Chihiro Aikawa, Takashi Nozawa, Ichiro Nakagawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Group A Streptoccocus
internalization
CAV1 (caveolin-1)
NAD-glycohydrolase
Streptolysin O (SLO)
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00398/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00398/full

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