Clinical significance of serum levels of matrix metalloproteinase 2 (MMP-2) and its tissue inhibitor (TIMP-2) in gastric cancer

Matrix metalloproteinase 2 (MMP-2) is able to degrade type IV collagen, and thus plays a key role in the migration of tumor cells. MMP-2 activity is inhibited by its tissue inhibitor (TIMP-2). The imbalance between MMPs and TIMPs may facilitate progression of cancer cells. The aim of this study was...

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Bibliographic Details
Main Authors: Maciej Szmitkowski, Bogusław Kędra, Mariusz Gryko, Marta Łukaszewicz-Zając, Barbara Mroczko
Format: Article
Language:English
Published: Via Medica 2011-04-01
Series:Folia Histochemica et Cytobiologica
Subjects:
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/4153