Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development

Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development

Summary: Human hematopoiesis is a dynamic process that starts in utero 18–21 days post-conception. Understanding the site- and stage-specific variation in hematopoiesis is important if we are to understand the origin of hematological disorders, many of which occur at specific points in the human lif...

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Bibliographic Details
Main Authors: Anindita Roy, Guanlin Wang, Deena Iskander, Sorcha O’Byrne, Natalina Elliott, Jennifer O’Sullivan, Gemma Buck, Elisabeth F. Heuston, Wei Xiong Wen, Alba Rodriguez Meira, Peng Hua, Anastasios Karadimitris, Adam J. Mead, David M. Bodine, Irene Roberts, Bethan Psaila, Supat Thongjuea
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Cell Reports
Subjects:
hematopoiesis
single-cell genomics
human development
stem/progenitor cells
single-cell RNA sequencing analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721011451

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http://www.sciencedirect.com/science/article/pii/S2211124721011451

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