Tandem‐Mass‐Tag Based Proteomic Analysis Facilitates Analyzing Critical Factors of Porous Silicon Nanoparticles in Determining Their Biological Responses under Diseased Condition

Tandem‐Mass‐Tag Based Proteomic Analysis Facilitates Analyzing Critical Factors of Porous Silicon Nanoparticles in Determining Their Biological Responses under Diseased Condition

Abstract The analysis of nanoparticles’ biocompatibility and immunogenicity is mostly performed under a healthy condition. However, more clinically relevant evaluation conducted under pathological condition is less known. Here, the immunogenicity and bio–nano interactions of porous silicon nanoparti...

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Bibliographic Details
Main Authors: Yunzhan Li, Zehua Liu, Li Li, Wenhua Lian, Yaohui He, Elbadry Khalil, Ermei Mäkilä, Wenzhong Zhang, Giulia Torrieri, Xueyan Liu, Jingyi Su, Yuanming Xiu, Flavia Fontana, Jarno Salonen, Jouni Hirvonen, Wen Liu, Hongbo Zhang, Hélder A. Santos, Xianming Deng
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Advanced Science
Subjects:
acute liver inflammation
immunogenicity
porous silicon
protein corona
R‐language
Online Access:https://doi.org/10.1002/advs.202001129

Internet

https://doi.org/10.1002/advs.202001129

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