On the Single-Crystal Structure of Tenofovir Alafenamide Mono-Fumarate: A Metastable Phase Featuring a Mixture of Co-Crystal and Salt

Tenofovir alafenamide (TAF) is a prodrug of tenofovir as a potent nucleotide reverse transcriptase inhibitor. It serves as the key component of Genvoya<sup>®</sup> for the first-line treatment of human immunodeficiency virus infection (HIV) and is the active component of Vemlidy<sup&g...

Full description

Bibliographic Details
Main Authors: Jian-Wei Wang, Lu Liu, Ka-Xi Yu, Hong-Zhen Bai, Jun Zhou, Wen-Hua Zhang, Xiurong Hu, Guping Tang
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/23/9213