Association of nuclear-localized Nemo-like kinase with heat-shock protein 27 inhibits apoptosis in human breast cancer cells.

Nemo-like kinase (NLK), a proline-directed serine/threonine kinase regulated by phosphorylation, can be localized in the cytosol or in the nucleus. Whether the localization of NLK can affect cell survival or cell apoptosis is yet to be disclosed. In the present study we found that NLK was mainly loc...

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Bibliographic Details
Main Authors: Gina Shaw-Hallgren, Katarzyna Chmielarska Masoumi, Reihaneh Zarrizi, Ulf Hellman, Per Karlsson, Khalil Helou, Ramin Massoumi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4015990?pdf=render