Chronic Myeloid Leukemia with e19a2 BCR-ABL1 Transcripts and Marked Thrombocytosis: The Role of Molecular Monitoring

While most patients with chronic myeloid leukemia (CML) express either e13a2 or e14a2 BCR-ABL1 transcripts, a significant minority expresses variant transcripts, of which e19a2 is the most common. Although considered to have a relatively favourable outcome, reported responses to tyrosine kinase inhi...

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Bibliographic Details
Main Authors: Stephen E. Langabeer, Sarah L. McCarron, Johanna Kelly, Janusz Krawczyk, Suzanne McPherson, Kanthi Perera, Philip T. Murphy
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2012/458716