The Cytotoxic Effect of the Benzene Metabolite Hydroquinone is Mediated by the Modulation of MDR1 Expression via the NF-κB Signaling Pathway

The Cytotoxic Effect of the Benzene Metabolite Hydroquinone is Mediated by the Modulation of MDR1 Expression via the NF-κB Signaling Pathway

Background/Aims: Benzene is a toxic chemical whose leukemogenic effects have been studied for decades. The mechanisms of benzene-induced toxicity and leukemogenicity are not fully understood, although the involvement of several pathways has been suggested, including oxidative stress, DNA damage, cel...

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Bibliographic Details
Main Authors: Jianshu Huang, Mingdong Zhao, Xiuju Li, Li Ma, Jihong Zhang, Jimin Shi, Bing Li, Wei Fan, Yuanling Zhou
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Hydroquinone
MDR1
NF-κB
Online Access:http://www.karger.com/Article/FullText/430379

Internet

http://www.karger.com/Article/FullText/430379

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