Tau overexpression impacts a neuroinflammation gene expression network perturbed in Alzheimer's disease.

Tau overexpression impacts a neuroinflammation gene expression network perturbed in Alzheimer's disease.

Filamentous inclusions of the microtubule-associated protein, tau, define a variety of neurodegenerative diseases known as tauopathies, including Alzheimer's disease (AD). To better understand the role of tau-mediated effects on pathophysiology and global central nervous system function, we ext...

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Bibliographic Details
Main Authors: Paul D Wes, Amy Easton, John Corradi, Donna M Barten, Nino Devidze, Lynn B DeCarr, Amy Truong, Aiqing He, Nestor X Barrezueta, Craig Polson, Clotilde Bourin, Marianne E Flynn, Stefanie Keenan, Regina Lidge, Jere Meredith, Joanne Natale, Sethu Sankaranarayanan, Greg W Cadelina, Charlie F Albright, Angela M Cacace
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4143352?pdf=render

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http://europepmc.org/articles/PMC4143352?pdf=render

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