Flavonoids Targeting HIF-1: Implications on Cancer Metabolism

Flavonoids Targeting HIF-1: Implications on Cancer Metabolism

Tumor hypoxia is described as an oxygen deprivation in malignant tissue. The hypoxic condition is a consequence of an imbalance between rapidly proliferating cells and a vascularization that leads to lower oxygen levels in tumors. Hypoxia-inducible factor 1 (HIF-1) is an essential transcription fact...

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Bibliographic Details
Main Authors: Marek Samec, Alena Liskova, Lenka Koklesova, Sandra Mersakova, Jan Strnadel, Karol Kajo, Martin Pec, Kevin Zhai, Karel Smejkal, Sepideh Mirzaei, Kiavash Hushmandi, Milad Ashrafizadeh, Luciano Saso, Aranka Brockmueller, Mehdi Shakibaei, Dietrich Büsselberg, Peter Kubatka
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
cancer
Warburg effect
HIF-1
flavonoids
Online Access:https://www.mdpi.com/2072-6694/13/1/130

Internet

https://www.mdpi.com/2072-6694/13/1/130

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