Epimutations, Inheritance and Causes of Aberrant DNA Methylation in Cancer

<p>Abstract</p> <p>Epigenetic aberrations such as global hypomethylation and gene-specific hypermethylation are key events that underlie tumour development. Such scenarios are brought about by the loss of control of methylation patterns which typically are reversed in neoplasia in...

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Bibliographic Details
Main Authors: Mossman David, Scott Rodney J
Format: Article
Language:English
Published: BMC 2006-05-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Online Access:http://www.hccpjournal.com/content/4/2/75