E2F4 promotes neuronal regeneration and functional recovery after spinal cord injury in zebrafish

E2F4 promotes neuronal regeneration and functional recovery after spinal cord injury in zebrafish

Mammals exhibit poor recovery after spinal cord injury (SCI), whereas non-mammalian vertebrates exhibit significant spontaneous recovery after SCI. The mechanisms underlying this difference have not been fully elucidated; therefore, the purpose of this study was to investigate these mechanisms. Usin...

Full description

Bibliographic Details
Main Authors: Yuhei eNishimura, Shota eSasagawa, Yuka eHayakawa, Soichiro eMurakami, Yoshifumi eAshikawa, Mizuki eYuge, Shiko eOkabe, Koki eKawaguchi, Reiko eKawase, TOSHIO eTANAKA
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Pharmacology
Subjects:
E2F4 Transcription Factor
Zebrafish
spinal cord injury
comparative transcriptomics
Systems Pharmacology
DREAM complex
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00119/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00119/full

Similar Items