Functional characterization and evaluation of in vitro protective efficacy of murine monoclonal antibodies BURK24 and BURK37 against Burkholderia pseudomallei.

Burkholderia pseudomallei, the causative agent of melioidosis has been recognized by CDC as a category B select agent. Although substantial efforts have been made for development of vaccine molecules against the pathogen, significant hurdles still remain. With no licensed vaccines available and high...

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Bibliographic Details
Main Authors: Bhavani V Peddayelachagiri, Soumya Paul, Shivakiran S Makam, Radhika M Urs, Joseph J Kingston, Urmil Tuteja, Murali H Sripathy, Harsh V Batra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24614539/?tool=EBI