SOX2 regulates acinar cell development in the salivary gland

SOX2 regulates acinar cell development in the salivary gland

Acinar cells play an essential role in the secretory function of exocrine organs. Despite this requirement, how acinar cells are generated during organogenesis is unclear. Using the acini-ductal network of the developing human and murine salivary gland, we demonstrate an unexpected role for SOX2 and...

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Bibliographic Details
Main Authors: Elaine Emmerson, Alison J May, Sara Nathan, Noel Cruz-Pacheco, Carlos O Lizama, Lenka Maliskova, Ann C Zovein, Yin Shen, Marcus O Muench, Sarah M Knox
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-06-01
Series:eLife
Subjects:
organogenesis
SOX2
acinar cells
epithelial morphogenesis
parasympathetic nerves
Online Access:https://elifesciences.org/articles/26620

Internet

https://elifesciences.org/articles/26620

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