The effect of bone marrow-derived mesenchymal stem cell co-transplantation with hematopoietic stem cells on liver fibrosis alleviation and survival in patients with class III β-thalassemia major

The effect of bone marrow-derived mesenchymal stem cell co-transplantation with hematopoietic stem cells on liver fibrosis alleviation and survival in patients with class III β-thalassemia major

Abstract Background Hepatic fibrosis is a common complication in transfusion-dependent thalassemia patients. Data on the co-transplantation of mesenchymal stem cells (MSCs) with hematopoietic stem cells (HSCs) in beta-thalassemia major patients are scarce. Therefore, we aimed to evaluate the effect...

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Bibliographic Details
Main Authors: Tahereh Rostami, Amir Kasaeian, Nasrollah Maleki, Mohsen Nikbakht, Azadeh Kiumarsi, Seyed Mohammad Tavangar, Amir Pejman Hashemi Taheri, Seied Asadollah Mousavi, Ardeshir Ghavamzadeh
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Stem Cell Research & Therapy
Subjects:
Hematopoietic stem cells
Mesenchymal stem cells
Beta-thalassemia
Liver fibrosis
Outcome
Online Access:https://doi.org/10.1186/s13287-021-02242-8

Internet

https://doi.org/10.1186/s13287-021-02242-8

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