Evaluating the Information Content of Shallow Shotgun Metagenomics

A common refrain in recent microbiome-related academic meetings is that the field needs to move away from broad taxonomic surveys using 16S sequencing and toward more powerful longitudinal studies using shotgun sequencing. However, performing deep shotgun sequencing in large longitudinal studies rem...

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Bibliographic Details
Main Authors: Benjamin Hillmann, Gabriel A. Al-Ghalith, Robin R. Shields-Cutler, Qiyun Zhu, Daryl M. Gohl, Kenneth B. Beckman, Rob Knight, Dan Knights
Format: Article
Published: American Society for Microbiology 2018-11-01
Online Access:https://doi.org/10.1128/mSystems.00069-18