Clobetasol Modulates Adult Neural Stem Cell Growth via Canonical Hedgehog Pathway Activation

Clobetasol Modulates Adult Neural Stem Cell Growth via Canonical Hedgehog Pathway Activation

Sonic hedgehog (Shh) signaling is a key pathway within the central nervous system (CNS), during both development and adulthood, and its activation via the 7-transmembrane protein Smoothened (Smo) may promote neuroprotection and restoration during neurodegenerative disorders. Shh signaling may also b...

Full description

Bibliographic Details
Main Authors: Nunzio Vicario, Joshua D. Bernstock, Federica M. Spitale, Cesarina Giallongo, Maria A.S. Giunta, Giovanni Li Volti, Massimo Gulisano, Giampiero Leanza, Daniele Tibullo, Rosalba Parenti, Rosario Gulino
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
neural stem cell (NSC)
steroids
clobetasol
sonic hedgehog signaling (Shh)
smoothened (Smo)
Gli
stem cell proliferation
Online Access:https://www.mdpi.com/1422-0067/20/8/1991

Internet

https://www.mdpi.com/1422-0067/20/8/1991

Similar Items