Mitochondrial Sequestration and Ca2+-Dependent Release of Cytosolic Zn2+ Loads in Cortical Neurons
The endogenous divalent cations, Ca2+ and Zn2+, are both highly toxic upon excessive glutamate triggered intracellular accumulation. Given apparent parallels in their neurotoxic mechanisms, the present study aimed to explore interactions between these cations, by examining effects of moderate intrac...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2002-07-01
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Series: | Neurobiology of Disease |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996102904936 |