Protection of retinal function and morphology in MNU-induced retinitis pigmentosa rats by ALDH2: an in-vivo study

Protection of retinal function and morphology in MNU-induced retinitis pigmentosa rats by ALDH2: an in-vivo study

Abstract Background Retinitis pigmentosa (RP) is a kind of inherited retinal degenerative diseases characterized by the progressive loss of photoreceptors. RP has been a conundrum without satisfactory countermeasures in clinic until now. Acetaldehyde dehydrogenase 2 (ALDH2), a major enzyme involved...

Full description

Bibliographic Details
Main Authors: Weiming Yan, Pan Long, Dongyu Wei, Weihua Yan, Xiangrong Zheng, Guocang Chen, Jiancong Wang, Zuoming Zhang, Tao Chen, Meizhu Chen
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Ophthalmology
Subjects:
ALDH2
Retinitis pigmentosa
Electroretinogram
Photoreceptor degeneration
SIRT1
Endoplasmic reticulum stress
Online Access:http://link.springer.com/article/10.1186/s12886-020-1330-8

Internet

http://link.springer.com/article/10.1186/s12886-020-1330-8

Similar Items