Mulberry polyphenols induce cell cycle arrest of vascular smooth muscle cells by inducing NO production and activating AMPK and p53

Mulberry polyphenols induce cell cycle arrest of vascular smooth muscle cells by inducing NO production and activating AMPK and p53

Proliferation/migration of vascular smooth muscle cells (VSMCs) plays vital roles in the pathogenesis of atherosclerosis and restenosis after percutaneous coronary intervention. Water extracts from mulberry fruit can inhibit VSMCs proliferation and migration and thereby atherosclerosis. In the prese...

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Bibliographic Details
Main Authors: Kuei-Chuan Chan, Hui-Pei Huang, Hsieh-Hsun Ho, Chien-Ning Huang, Ming-Cheng Lin, Chau-Jong Wang
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Journal of Functional Foods
Subjects:
Mulberry polyphenol extracts
Cell cycle arrest
Nitric oxide
AMPK
p53
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615001504

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http://www.sciencedirect.com/science/article/pii/S1756464615001504

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