TLR4-NOX2 axis regulates the phagocytosis and killing of Mycobacterium tuberculosis by macrophages

Abstract Background Macrophages stand at the forefront of both innate and adapted immunity through their capacities to recognize, engulf, and eliminate foreign particles, and to stimulate adapted immune cells. They are also involved in controlling pro- and anti-inflammatory pathways. Macrophage acti...

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Bibliographic Details
Main Authors: Jingzhu Lv, Xiaoyan He, Hongtao Wang, Zhaohua Wang, Gabriel T. Kelly, Xiaojing Wang, Yin Chen, Ting Wang, Zhongqing Qian
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Pulmonary Medicine
Subjects:
TB
TLR
Online Access:http://link.springer.com/article/10.1186/s12890-017-0517-0