Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif.

The corticotropin-releasing hormone receptor type 1 (CRHR1) plays an important role in orchestrating neuroendocrine, behavioral, and autonomic responses to stress. To identify molecules capable of directly modulating CRHR1 signaling, we performed a yeast-two-hybrid screen using the C-terminal intrac...

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Bibliographic Details
Main Authors: Julia Bender, Maik Engeholm, Marion S Ederer, Johannes Breu, Thor C Møller, Stylianos Michalakis, Tamas Rasko, Erich E Wanker, Martin Biel, Karen L Martinez, Wolfgang Wurst, Jan M Deussing
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4564177?pdf=render