Genetic variants of TSLP and asthma in an admixed urban population.

Genetic variants of TSLP and asthma in an admixed urban population.

Thymic stromal lymphopoietin (TSLP), an IL7-like cytokine produced by bronchial epithelial cells is upregulated in asthma and induces dendritic cell maturation supporting a Th2 response. Environmental pollutants, including tobacco smoke and diesel exhaust particles upregulate TSLP suggesting that TS...

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Bibliographic Details
Main Authors: Mengling Liu, Linda Rogers, Qinyi Cheng, Yongzhao Shao, Maria Elena Fernandez-Beros, Joel N Hirschhorn, Helen N Lyon, Zofia K Z Gajdos, Sailaja Vedantam, Peter Gregersen, Michael F Seldin, Bertram Bleck, Adaikalavan Ramasamy, Anna-Liisa Hartikainen, Marjo-Riitta Jarvelin, Mikko Kuokkanen, Tarja Laitinen, Johan Eriksson, Terho Lehtimäki, Olli T Raitakari, Joan Reibman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3178593?pdf=render

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http://europepmc.org/articles/PMC3178593?pdf=render

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