Investigating the Effects of Tissue-Specific Extracellular Matrix on the Adipogenic and Osteogenic Differentiation of Human Adipose-Derived Stromal Cells Within Composite Hydrogel Scaffolds

Investigating the Effects of Tissue-Specific Extracellular Matrix on the Adipogenic and Osteogenic Differentiation of Human Adipose-Derived Stromal Cells Within Composite Hydrogel Scaffolds

While it has been postulated that tissue-specific bioscaffolds derived from the extracellular matrix (ECM) can direct stem cell differentiation, systematic comparisons of multiple ECM sources are needed to more fully assess the benefits of incorporating tissue-specific ECM in stem cell culture and d...

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Bibliographic Details
Main Authors: Arthi Shridhar, Brian G. Amsden, Elizabeth R. Gillies, Lauren E. Flynn
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
adipose-derived stromal cells
cell culture models
decellularization
extracellular matrix (ECM)
hydrogel composites
methacrylated chondroitin sulfate
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00402/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2019.00402/full

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