Molecular docking, synthesis and in vitro antimalarial evaluation of certain novel curcumin analogues

ABSTRACT The receptor protein PfATP6 has been identified as the common target of artemisinin and curcumin. The work was initiated to assess the antimalarial activity of six curcumin derivatives based on their binding affinities and correlating the in silico docking outcome with in vitro antimalarial...

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Bibliographic Details
Main Authors: Chandrajit Dohutia, Dipak Chetia, Kabita Gogoi, Dibya Ranjan Bhattacharyya, Kishore Sarma
Format: Article
Language:English
Published: Universidade de São Paulo 2018-01-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000400603&lng=en&tlng=en