Drug–Drug Compatibility Evaluation of Sulfasalazine and Folic Acid for Fixed-Dose Combination Development Using Various Analytical Tools

Drug–Drug Compatibility Evaluation of Sulfasalazine and Folic Acid for Fixed-Dose Combination Development Using Various Analytical Tools

The simultaneous administration of sulfasalazine and folic acid is regular practice in the therapy of inflammatory bowel diseases in order to maintain sufficient folate concentration in patients. Having multiple drugs in the therapy increases the possibility of patients failing adherence, thus unint...

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Bibliographic Details
Main Authors: Mario-Livio Jeličić, Edvin Brusač, Stanislav Kurajica, Matija Cvetnić, Daniela Amidžić Klarić, Biljana Nigović, Ana Mornar
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Pharmaceutics
Subjects:
sulfasalazine
folic acid
fixed-dose combination
physicochemical compatibility
thermal techniques
spectroscopy
Online Access:https://www.mdpi.com/1999-4923/13/3/400

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https://www.mdpi.com/1999-4923/13/3/400

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