Influenza “Trains” the Host for Enhanced Susceptibility to Secondary Bacterial Infection

Influenza “Trains” the Host for Enhanced Susceptibility to Secondary Bacterial Infection

Enhanced susceptibility to 2° bacterial infections following infection with influenza virus is a global health concern that accounts for many hospitalizations and deaths, particularly during pandemics. The complexity of the impaired host immune response during 2° bacterial infection has been widely...

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Bibliographic Details
Main Authors: Kari Ann Shirey, Darren J. Perkins, Wendy Lai, Wei Zhang, Lurds R. Fernando, Fabian Gusovsky, Jorge C. G. Blanco, Stefanie N. Vogel
Format: Article
Language:English
Published: American Society for Microbiology 2019-05-01
Series:mBio
Subjects:
IFN-β
MRSA
Streptococcus pneumoniae
TLR4
cotton rats
influenza
macrophage training
secondary bacterial infection
Online Access:https://doi.org/10.1128/mBio.00810-19

Internet

https://doi.org/10.1128/mBio.00810-19

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