Development of a Fluorescent Multiplex Assay for Detection of MSI-High Tumors

Determining whether a tumor exhibits microsatellite instability (MSI) is useful in identifying patients with hereditary non-polyposis colorectal cancer and sporadic gastrointestinal cancers with defective DNA mismatch repair (MMR). The assessment of MSI status aids in establishing a clinical prognos...

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Bibliographic Details
Main Authors: Jeffery W. Bacher, Laura A. Flanagan, Regenia L. Smalley, Nadine A. Nassif, Lawrence J. Burgart, Richard B. Halberg, Wael M. Abdel Megid, Stephen N. Thibodeau
Format: Article
Language:English
Published: Hindawi Limited 2004-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2004/136734