Pathway Instability Is an Effective New Mutation-Based Type of Cancer Biomarkers

Pathway Instability Is an Effective New Mutation-Based Type of Cancer Biomarkers

DNA mutations play a crucial role in cancer development and progression. Mutation profiles vary dramatically in different cancer types and between individual tumors. Mutations of several individual genes are known as reliable cancer biomarkers, although the number of such genes is tiny and does not...

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Bibliographic Details
Main Authors: Marianna A. Zolotovskaia, Maxim I. Sorokin, Sergey A. Roumiantsev, Nikolay M. Borisov, Anton A. Buzdin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Oncology
Subjects:
cancer
DNA mutation
molecular pathways
biomarker
pathway instability
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00658/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2018.00658/full

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