Cerebello-Cortical Alterations Linked to Cognitive and Social Problems in Patients With Spastic Paraplegia Type 7: A Preliminary Study

Cerebello-Cortical Alterations Linked to Cognitive and Social Problems in Patients With Spastic Paraplegia Type 7: A Preliminary Study

Spastic paraplegia type 7 (SPG7), which represents one of the most common forms of autosomal recessive spastic paraplegia (MIM#607259), often manifests with a complicated phenotype, characterized by progressive spastic ataxia with evidence of cerebellar atrophy on brain MRI. Recent studies have docu...

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Bibliographic Details
Main Authors: Michela Lupo, Giusy Olivito, Silvia Clausi, Libera Siciliano, Vittorio Riso, Marco Bozzali, Filippo M. Santorelli, Gabriella Silvestri, Maria Leggio
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Neurology
Subjects:
spastic paraplegia type 7
cerebellum
cognition
social skills
CCAS
functional connectivity
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00082/full

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https://www.frontiersin.org/article/10.3389/fneur.2020.00082/full

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