The Proton-Boron Reaction Increases the Radiobiological Effectiveness of Clinical Low- and High-Energy Proton Beams: Novel Experimental Evidence and Perspectives

The Proton-Boron Reaction Increases the Radiobiological Effectiveness of Clinical Low- and High-Energy Proton Beams: Novel Experimental Evidence and Perspectives

Protontherapy is a rapidly expanding radiotherapy modality where accelerated proton beams are used to precisely deliver the dose to the tumor target but is generally considered ineffective against radioresistant tumors. Proton-Boron Capture Therapy (PBCT) is a novel approach aimed at enhancing proto...

Full description

Bibliographic Details
Main Authors: Pavel Bláha, Chiara Feoli, Stefano Agosteo, Marco Calvaruso, Francesco Paolo Cammarata, Roberto Catalano, Mario Ciocca, Giuseppe Antonio Pablo Cirrone, Valeria Conte, Giacomo Cuttone, Angelica Facoetti, Giusi Irma Forte, Lorenzo Giuffrida, Giuseppe Magro, Daniele Margarone, Luigi Minafra, Giada Petringa, Gaia Pucci, Valerio Ricciardi, Enrico Rosa, Giorgio Russo, Lorenzo Manti
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
protontherapy
chromosome aberrations
proton-boron (B) fusion-enhanced proton therapy (PBFEPT)
BSH
alpha-particle
cancer cell killing
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.682647/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.682647/full

Similar Items