INSULIN-LIKE GROWTH FACTOR (IGF)-1 IN CNS AND CEREBROVASCULAR AGING

INSULIN-LIKE GROWTH FACTOR (IGF)-1 IN CNS AND CEREBROVASCULAR AGING

Insulin-like growth factor-1 (IGF-1) is an important anabolic hormone that decreases with age. In the past two decades extensive research has determined that the reduction in IGF-1 is an important component of the age-related decline in cognitive function in multiple species including humans. Defici...

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Bibliographic Details
Main Authors: William E Sonntag, Ferenc eDeak, Nicole eAshpole, Anna eCsiszar, Peter eToth, Willard eFreeman, Zoltan eUngvari
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
Aging
Synapses
cognitive decline
IGF-1
vasculature
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2013.00027/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2013.00027/full

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