Phage Display Analysis of Monoclonal Antibody Binding to Anthrax Toxin Lethal Factor

Phage Display Analysis of Monoclonal Antibody Binding to Anthrax Toxin Lethal Factor

AVR1674 and AVR1675 are monoclonal antibodies (mAbs) that bind with high specificity to anthrax toxin lethal factor (LF) and lethal toxin (LTx). These mAbs have been used as pivotal reagents to develop anthrax toxin detection tests using mass spectrometry. The mAbs were demonstrated to bind LF with...

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Bibliographic Details
Main Authors: Jason M. Goldstein, Joo Lee, Xiaoling Tang, Anne E. Boyer, John R. Barr, Dennis A. Bagarozzi Jr., Conrad P. Quinn
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Toxins
Subjects:
Bacillus anthracis
anthrax
monoclonal antibody
phage display
epitope
lethal factor
protective antigen
mass spectrometry
Online Access:https://www.mdpi.com/2072-6651/9/7/221

Internet

https://www.mdpi.com/2072-6651/9/7/221

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