Preliminary assessment of nanopore-based metagenomic sequencing for the diagnosis of prosthetic joint infection

Preliminary assessment of nanopore-based metagenomic sequencing for the diagnosis of prosthetic joint infection

Objectives: Pathogen identification is crucial for the diagnosis and management of periprosthetic joint infection (PJI). Although culturing methods are the foundation of pathogen detection in PJI, false-negative results often occur. Oxford nanopore sequencing (ONS) is a promising alternative for det...

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Bibliographic Details
Main Authors: Chao-xin Wang, Zida Huang, Wei Fang, Zijie Zhang, Xinyu Fang, Wenbo Li, Bin Yang, Luyao Chen, Xiangzhi Liang, Huan Hu, Duozhi Shi, Shela Lee, Wenming Zhang
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:International Journal of Infectious Diseases
Subjects:
Prosthetic joint infection
Metagenomic sequencing
Nanopore sequencing
Metagenomic next-generation sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971220303519

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http://www.sciencedirect.com/science/article/pii/S1201971220303519

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