The promigratory activity of the matricellular protein galectin-3 depends on the activation of PI-3 kinase.

The promigratory activity of the matricellular protein galectin-3 depends on the activation of PI-3 kinase.

Expression of galectin-3 is associated with sarcoma progression, invasion and metastasis. Here we determined the role of extracellular galectin-3 on migration of sarcoma cells on laminin-111. Cell lines from methylcholanthrene-induced sarcomas from both wild type and galectin-3(-/-) mice were establ...

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Bibliographic Details
Main Authors: Fabiana H M Melo, Diego Butera, Mara de Souza Junqueira, Daniel K Hsu, Ana Maria Moura da Silva, Fu-Tong Liu, Marinilice F Santos, Roger Chammas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3247242?pdf=render

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http://europepmc.org/articles/PMC3247242?pdf=render

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