Vitexin induces apoptosis through mitochondrial pathway and PI3K/Akt/mTOR signaling in human non-small cell lung cancer A549 cells

Vitexin induces apoptosis through mitochondrial pathway and PI3K/Akt/mTOR signaling in human non-small cell lung cancer A549 cells

Abstract Background Currently, the prognosis of patients with non-small cell lung cancer (NSCLC) remains dismal; hence, it is critical to identify effective anti-NSCLC agents with limited side effects. This study aimed to evaluate the therapeutic potential of flavonoid compound vitexin in human NSCL...

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Bibliographic Details
Main Authors: Xiaoli Liu, Qingfeng Jiang, Huaimin Liu, Suxia Luo
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Biological Research
Subjects:
Non-small cell lung cancer
Vitexin
Mitochondrial dysfunction
PI3K/Akt/mTOR signaling
Online Access:http://link.springer.com/article/10.1186/s40659-019-0214-y

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http://link.springer.com/article/10.1186/s40659-019-0214-y

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