Cellular Tight Junctions Prevent Effective Campylobacter jejuni Invasion and Inflammatory Barrier Disruption Promoting Bacterial Invasion from Lateral Membrane in Polarized Intestinal Epithelial Cells

Cellular Tight Junctions Prevent Effective Campylobacter jejuni Invasion and Inflammatory Barrier Disruption Promoting Bacterial Invasion from Lateral Membrane in Polarized Intestinal Epithelial Cells

Campylobacter jejuni invasion is closely related to C. jejuni pathogenicity. The intestinal epithelium contains polarized epithelial cells that form tight junctions (TJs) to provide a physical barrier against bacterial invasion. Previous studies indicated that C. jejuni invasion of non-polarized cel...

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Bibliographic Details
Main Authors: Sho Hatayama, Takaaki Shimohata, Sachie Amano, Junko Kido, Anh Q. Nguyen, Yuri Sato, Yuna Kanda, Aya Tentaku, Shiho Fukushima, Mutsumi Nakahashi, Takashi Uebanso, Kazuaki Mawatari, Akira Takahashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Campylobacter jejuni
Tight Junctions (TJs)
lipid rafts
cell invasion
lateral part of epithelial cells
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2018.00015/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2018.00015/full

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