Therapeutic Potential of Flavonoids in Pain and Inflammation: Mechanisms of Action, Pre-Clinical and Clinical Data, and Pharmaceutical Development

Therapeutic Potential of Flavonoids in Pain and Inflammation: Mechanisms of Action, Pre-Clinical and Clinical Data, and Pharmaceutical Development

Pathological pain can be initiated after inflammation and/or peripheral nerve injury. It is a consequence of the pathological functioning of the nervous system rather than only a symptom. In fact, pain is a significant social, health, and economic burden worldwide. Flavonoids are plant derivative co...

Full description

Bibliographic Details
Main Authors: Camila R. Ferraz, Thacyana T. Carvalho, Marília F. Manchope, Nayara A. Artero, Fernanda S. Rasquel-Oliveira, Victor Fattori, Rubia Casagrande, Waldiceu A. Verri
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
clinical trials
natural products
hyperalgesia
allodynia
analgesia
flavonoid
hypersensitivity
inflammation
cytokines
nf-kb
Online Access:https://www.mdpi.com/1420-3049/25/3/762

Internet

https://www.mdpi.com/1420-3049/25/3/762

Similar Items