Synthesis and Antimicrobial Activity of Some New 1,3,4-Thiadiazole and 1,2,4-Triazole Compounds Having a D,L-Methionine Moiety

Synthesis and Antimicrobial Activity of Some New 1,3,4-Thiadiazole and 1,2,4-Triazole Compounds Having a D,L-Methionine Moiety

New 1,3,4-thiadiazole, 5a-e, and 1,2,4-triazolecompounds 6a-c, containing a D,L-methionine moiety were synthesized by intramolecular cyclization of 1,4-disubstituted thiosemicarbazides 4a-e in acid and alkaline media, respectively. The potential antimicrobial effects of the synthesized compounds wer...

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Bibliographic Details
Main Authors: Aurel Pui, Marcel Popa, Valeriu Sunel, Lenuta Profire, Otilia Pintilie
Format: Article
Language:English
Published: MDPI AG 2007-01-01
Series:Molecules
Subjects:
1
3
4-Thiadiazole
2
4-triazole
thiosemicarbazide
D
L-methionine
antimicrobial activity
Online Access:http://www.mdpi.com/1420-3049/12/1/103/

Internet

http://www.mdpi.com/1420-3049/12/1/103/

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