Synthesis and Biological Evaluation of 2,4-Diaminopyrimidine-Based Antifolate Drugs against Bacillus anthracis

Due to the innate ability of bacteria to develop resistance to available antibiotics, there is a critical need to develop new agents to treat more resilient strains. As a continuation of our research in this area, we have synthesized a series of racemic 2,4-diaminopyrimidine-based drug candidates,...

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Bibliographic Details
Main Authors: Baskar Nammalwar, N. Prasad Muddala, Christina R. Bourne, Mary Henry, Philip C. Bourne, Richard A. Bunce, Esther W. Barrow, K. Darrell Berlin, William W. Barrow
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/3/3231

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